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(19)

(11)

2 273 472

(13)

(51)

IPC

A61K9/20(2006-01-01)

A61K9/16(2006-01-01)

A61K47/10(2006-01-01)

A61K47/26(2006-01-01)

A61K31/51(2006-01-01)

A61K31/455(2006-01-01)

A61K31/167(2006-01-01)

A61K31/405(2006-01-01)

A61K31/135(2006-01-01)

A61K31/4704(2006-01-01)

A61K31/216(2006-01-01)

A61K31/5513(2006-01-01)

A61K31/515(2006-01-01)

A61K31/606(2006-01-01)

A61K31/43(2006-01-01)

A61K31/513(2006-01-01)

A61K31/401(2006-01-01)

A61K31/4422(2006-01-01)

A61K31/166(2006-01-01)

A61K31/404(2006-01-01)

(21) (22)

Application

2003114296/15, 2001-10-15

(24)

Start date

2001-10-15

(22)

Actual filing date

2001-10-15

(45)

Published

2006-04-10

(72)

Inventor

Nakagami KhiroakiKuno Josio

(73)

Holder

Dajiti Farmas'Jutikal Ko., Ltd.

MEDICINAL COMPOSITION DECOMPOSING IN MOUTH CAVITY RAPIDLY AND METHOD FOR ITS PREPARING Russian patent published in 2006 - IPC A61K9/20 A61K9/16 A61K47/10 A61K47/26 A61K31/51 A61K31/455 A61K31/167 A61K31/405 A61K31/135 A61K31/4704 A61K31/216 A61K31/5513 A61K31/515 A61K31/606 A61K31/43 A61K31/513 A61K31/401 A61K31/4422 A61K31/166 A61K31/404

Abstract RU 2273472 C2

FIELD: pharmaceutical technology, pharmacy.

SUBSTANCE: method involves addition sugar-alcohol and/or saccharide showing melting point by 5°C lower or above as compared with the first mentioned sugar-alcohol and/or saccharide to sugar-alcohol and/or saccharide followed by combined treatment of prepared powder by pressing and heating. Invention allows preparing medicinal compositions decomposing in mouth cavity rapidly being without water and showing light using owing to the presence of sufficient strength in preparing, transport in usual using. Method involves mixing, pressing and heating components that represent two or more sugar-alcohol and/or saccharide and active component wherein difference between melting points of one among two or more indicated sugar-alcohol and/or saccharide that shows the higher content and any remaining indicated two or more sugar-alcohol and/or saccharide is 5°C or above. Invention provides preparing strength rapidly soluble tablets.

EFFECT: improved preparing method, improved pharmaceutical properties of composition.

30 cl, 12 tbl, 28 ex

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RU 2 273 472 C2

Authors

Nakagami Khiroaki

Kuno Josio

Dates

2006-04-10—Published

2001-10-15—Filed