METHOD FOR DETERMINING BLOOD OXYMETHYL URACYL Russian patent published in 2006 - IPC G01N33/52 

Abstract RU 2276360 C2

FIELD: medicine.

SUBSTANCE: method involves making extraction with dimethyl sulfoxide mixed with water in 3:1 proportion in retort having backflow condenser on water bath during 1 h. The produced extract is filtered. The filtrate is chromatographically studied first in 5 cm high and 0.7 cm diameter columns with alumina and then in thin sorbent layer solvent system containing condensed ammonium and alcohol taken in 1:4 proportion. The eluate is subjected to spectrophotometric analysis at 278±2 nm. Oxymethyl uracyl quantity is determined from formula C=D x b/(E1%cvxa), where C is the substance concentration in %, D is the optical density, b is the dilution rate, E1%cv is the specific absorption index, a is the exact weighing in g.

EFFECT: high accuracy of blood oxymethyl uracyl control in treatment course.

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RU 2 276 360 C2

Authors

Plechev Vladimir Vjacheslavovich

Likhoded Vitalij Alekseevich

Timerbulatov Vil' Mamilovich

Golovastikova Zhanna Mikhajlovna

Shikova Julija Vital'Evna

Plecheva Dina Vladimirovna

Shikov Artem Nikolaevich

Brazhenko Mikhail Aleksandrovich

Elova Elena Vladimirovna

Chernov Nikolaj Vasil'Evich

Dates

2006-05-10Published

2004-06-24Filed