FIELD: medicine, dermatology.
SUBSTANCE: invention proposes oxygen-, sulfur or selenium-containing analogs of fatty acids in treatment of proliferative cutaneous disorders or for inhibition of proliferation and/or induction of keratinocytes differentiation, and a method for treatment of cutaneous disorders. Indicated analogs of fatty acids (in particular, tetradecylthioacetic acid and tetradecylselenoacetic acid) inhibit proliferation of NKH cells effectively and cause the strong expression of gene-markers of keratinocytes differentiation. Method provides improvement in desquamation and erythema, decreasing skin injury and stopping itching.
EFFECT: enhanced effectiveness and valuable medicinal properties of substances.
16 cl, 3 dwg, 4 ex
Authors
Dates
2006-05-20—Published
2001-09-27—Filed