ANALOGS OF FATTY ACIDS FOR TREATMENT OF PROLIFERATIVE CUTANEOUS DISORDERS Russian patent published in 2006 - IPC A61K31/231 A61K31/232 A61K31/20 A61K31/201 A61K31/202 A61P17/06 A61P17/08 A61P17/16 A61P35/00 

Abstract RU 2276602 C2

FIELD: medicine, dermatology.

SUBSTANCE: invention proposes oxygen-, sulfur or selenium-containing analogs of fatty acids in treatment of proliferative cutaneous disorders or for inhibition of proliferation and/or induction of keratinocytes differentiation, and a method for treatment of cutaneous disorders. Indicated analogs of fatty acids (in particular, tetradecylthioacetic acid and tetradecylselenoacetic acid) inhibit proliferation of NKH cells effectively and cause the strong expression of gene-markers of keratinocytes differentiation. Method provides improvement in desquamation and erythema, decreasing skin injury and stopping itching.

EFFECT: enhanced effectiveness and valuable medicinal properties of substances.

16 cl, 3 dwg, 4 ex

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RU 2 276 602 C2

Authors

Berge Rol'F

Kristiansen Karsten

Dates

2006-05-20Published

2001-09-27Filed