INTERFERON-CONTAINING AEROSOL COMPOSITION "NIKOFEN" Russian patent published in 2006 - IPC A61K9/12 A61K38/21 A61P31/00 

Abstract RU 2277904 C2

FIELD: pharmaceutical industry.

SUBSTANCE: invention provides composition containing 0.1-0.5% nicotinic acid, 0.01-0.05% olifen-containing preparation, 0.5-1 mln ME interferon, and solvent. Use of this composition allows interferon dose to be lowered in single time administration cases. Bioavailability and residence time in system bloodstream of preparation are increased. In addition, liver first passage effect is avoided as well as accompanying unfavorable reactions resulting in changed preparation structure. Preparation also alleviates inflammatory phenomena in focuses of primary virus contact with microorganism cells.

EFFECT: expanded therapeutical possibilities.

5 cl, 3 dwg, 3 tbl, 3 ex

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RU 2 277 904 C2

Authors

Vorobejchikov Evgenij Vladimirovich

Nikolaev Boris Petrovich

Jakovleva Ljudmila Jur'Evna

Egorova Tat'Jana Semenovna

Dates

2006-06-20Published

2004-05-05Filed