PHARMACEUTICAL COMPOSITION AND METHOD FOR PULMONARY ADMINISTRATION THEREOF Russian patent published in 2012 - IPC A61K47/40 A61K47/30 A61K9/12 A61K9/72 A61K9/14 A61K31/00 A61J3/02 A61P43/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine, namely pharmacology. A pharmaceutical composition contains an active component selected from a group of pharmacologically active substances: having an effect on a central nervous system, peripheral neurotransmitter processes, cardiovascular system, coagulation system, neoplastic processes, metabolic processes, showing antibacterial activity, an excipient, cyclodextrin as a component ensuring high bioavailability, and a component modulating a duration of the pharmacologically active substance representing polymer. The pharmaceutical composition is presented in the form of a powder of particle size within 0.4 to 2 mcm. A method for administration of the pharmaceutical composition provides the pulmonary oral administration in the form of a dry or liquid aerosol with mass median aerodynamic diameter 0.8 to 2.0 mcm and degree of polydispersity 0.8 to 2.0.

EFFECT: ensured effective delivery of the pharmacologically active substances in the systemic circulation and alveolar inhalations of min 75% of solid or liquid aerosol particles.

5 cl, 5 dwg, 4 ex