INTERFERON-CONTAINING COMPOSITION FOR THE TREATMENT OF CHRONIC DISEASES OF THE UPPER RESPIRATORY WAYS Russian patent published in 2023 - IPC A61K9/12 A61K38/21 A61K47/12 A61K47/20 A61K47/36 A61P11/00 

Abstract RU 2789513 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to an interferon-containing composition for the treatment of chronic polypous rhinosinusitis. Interferon-containing composition for the treatment of chronic polypous rhinosinusitis, containing recombinant interferon, acid and water, characterized in that it contains interferon α2b AND/OR gamma (γ) as an interferon, and contains succinic acid as an acid, while additionally dimethyl sulfoxide and chitosan in the following the content of components: interferon alpha and/or gamma - 0.5-1.5 million IU, succinic acid - 0.1-1.2 wt. %, chitosan - 0.1–1.0 wt. %, dimethyl sulfoxide - 0.01–0.1 wt. %, water - the rest in wt.%.

EFFECT: invention allows to increase the delay time of interferon in the nasal mucosa and reduce its entry into the systemic circulation.

1 cl, 8 dwg, 14 tbl, 4 ex

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Authors

Kravchenko Eduard Vitalevich

Skvortsov Nikita Vladislavovich

Bezrukova Evgeniya Valerevna

Vorobejchikov Evgenij Vladimirovich

Simbirtsev Andrej Semenovich

Dates

2023-02-06Published

2022-05-24Filed