INJECTABLE GALENIC COMPOSITION FOR USING IN DIAGNOSIS OR PHOTODYNAMIC THERAPY AND METHOD FOR ITS PREPARING Russian patent published in 2006 - IPC A61K31/555 A61P35/00 

Abstract RU 2278665 C2

FIELD: medicine, pharmacy.

SUBSTANCE: invention relates to the injectable galenic composition used in diagnosis or photodynamic therapy and to a method for its preparing. The composition comprises the following components: compound of the general formula (I) given in the invention description wherein R2 means hydrogen atom, hydroxyl group (-OH) or group -COOR4 wherein R4 means hydrogen atom or (C1-C12)-alkyl, or (C3-C12)-cycloalkyl; R3 means hydrogen atom, -OH or (C1-C12)-alkyl, or (C1-C12)-alkoxyl, and symbol * means asymmetric carbon atom in form of alkaline metal salt in the amount not exceeding 1 weight% to the total weight of the composition (10 mg/ml) as a photosensitizing agent and a filling agent in an aqueous phase comprising at least a mixture of benzyl alcohol and ethanol or propylene glycol as a solubilizing agent for a photosensitizing agent and a surface-active substance in the amount not exceeding 20 wt.-% to the total mass of the composition under condition that when Cremophore represents a surface-active substance then its amount must not exceed 5 weigh% to the total weight of the composition.

EFFECT: improved preparing method, valuable properties of composition.

18 cl, 7 tbl

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RU 2 278 665 C2

Authors

Brehn P'Er-Ehrve

Prjudom Alen

Barnu Zhan-Ljuk

Dates

2006-06-27Published

2002-07-05Filed