TRANSESTERIFICATION METHOD FOR PRODUCTION OF SYNTHETIC CHLOROPHYLL OR BACTERIOCHLOROPHYLL DERIVATIVES Russian patent published in 2005 - IPC

FIELD: biochemistry.

SUBSTANCE: invention relates to method for production of synthetic chlorophyll (Chl) or bacteriochlorophyll (Bchl) derivatives of general formula I , wherein X is O;. Claimed method includes interaction under anaerobic conditions of Chl, Bchl derivatives containing COOCH₃-group in C-13²-position and COOR³-group in C-17²-position in presence of tetraethyl orthotitanate. Further compounds of formula I wherein R¹ and R² are different radicals are obtained in aproton solvent such as peroxide-free tetrahydrofurane and dimethyl formamide, and compounds of formula I wherein R¹ and R² are the same ones are produced by using R¹OH as a solvent. Derivatives of present invention are useful as stabilizers, linkage/spacer for binding another acceptable molecules to Chl/Bchl macrocycle.

EFFECT: simplified method for production of various chlorophyll or bacteriochlorophyll derivatives.

13 cl, 3 ex, 2 tbl, 8 dwg