MATERIAL FOR OSTEOPLASTY AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2006 - IPC A61K35/32 A61L27/00 

FIELD: medicine, in particular stomatology, traumatology, orthopaedy, and surgical stomatology.

SUBSTANCE: claimed method includes bone tissue cleaning, sawing, defatting, treatment with urea solution, washing, drying, packing and sterilization, wherein after purification bone is sawed to produce slides of 0.1-2.0 cm thickness; treated with 2 % alkali solution washed, treated with 6 M urea solution, then with 3 % hydrogen peroxide; defatted in ethanol and chloroform mixture in ratio of 1:2 (wherein solution is replaced with fresh one not less than 2 times), treated with mixture of 1 % ammonium and 1 % ethanol in ratio of 1:1 (wherein solution is replaced with fresh one not less than 2 times) and saturated with sulfated glycosaminoglycanes up to 800-1500 mug/cm³, dried, packed and sterilized by radiation. Material of present invention is useful in biomaterial preparation, and as carrier for active agents, drugs, cells, as well as in plastic surgery for organ or tissue regeneration.

EFFECT: material containing non-demineralized collagen from bone tissue, sulfated glycosaminoglycanes and water with decreased antigenic characteristic and increased biocompatibility.

2 cl, 1 tbl, 3 ex