METHOD FOR OBTAINING OSTEOPLASTIC MATERIAL Russian patent published in 2017 - IPC A61L27/36 A61F2/28 B01D15/40 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine, namely to method for obtaining osteoplastic material. The method includes mechanical cleaning of bone from soft tissues and sawing cancellous bone, treatment with hypertonic sodium chloride solution with concentration 1-10% for 1-8 days, placement of material into ultrasonic bath with hydrogen peroxide solution with concentration 1-10% per 1-8 days, deep purification and delipidation by method of supercritical fluid extraction at temperature 20-70°C and pressure 1000-10000 psi for 30-500 minutes, demineralisation with hydrochloric acid 0.5-4 M for 15-300 minutes and lyophilisation for 1-48 hours.

EFFECT: invention makes it possible to perform deep and save purification of bone matrix with preservation of structure of bone matrix and native morphogenetic proteins, red.

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