METHOD FOR OBTAINING OSSEOUS ALLOTRANSPLANT FOR SUBSTITUTING DEFECTS OF CRANIAL BONES Russian patent published in 2006 - IPC A61K35/32 

FIELD: medicine, reconstructive surgery.

SUBSTANCE: the present innovation deals with obtaining osseous plastic material, in particular, to be applied in the field of oral surgery due to carrying out mechanical treatment, degreasing, demineralization, freezing, lyophilization and sterilization. As an allotransplant one should apply the bones of cranial arch. Demineralization should be conducted up to 83-94%, and freezing should be fulfilled in physiological solution at -30 - -35° C for about 24-72 h at 3-5-fold defrosting and change of physiological solution. The innovation enables to obtain an allogenic transplant of decreased antigenic properties and being capable to temporarily substitute the defects of cranial bones of different etiology, sizes and localization followed by development of its own bony tissue of organotopic structure.

EFFECT: higher efficiency.

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