METHOD FOR OBTAINING XENOTRANSPLANTS FOR OPHTHALMOLOGY Russian patent published in 2006 - IPC A61F2/14 A61F9/00 A61K35/12 A61P27/02 

Abstract RU 2281061 C1

FIELD: medicine, ophthalmology.

SUBSTANCE: the present innovation deals with creating safe and efficient heteroplastic material for treating progressing myopia, stabilization of dry maculodystrophy and manufacturing antiglaucomatous drainages at maximal decrease of antigenic properties and guaranteed sterility of biomaterial that provides the absence of post-operational complications (chemosis, tenonitis, pridocyclitis) at operative therapy of progressing myopia and guarantees stabilization of myopia progressing, the stabilization of pathological processes at dry maculodystrophy, normalization of intra-ocular pressure at operative treatment of glaucoma at applying the drainage out of the material suggested. In the course of the method in question one should treat cattle pericardium after mechanical purification with 10%-ammonia solution for about 4-5 h, washed with distilled water followed by a 4-fold freezing at -10-12° C and defrosting at +40-45° C, for 7.5 h it should be treated with 6%-hydrogen peroxide solution at +15° C, after cutting the material it should be treated with ultrasound to repeat the whole procedure at mixing device, then material should be dehydrated in alcohols of initial concentration ranged 30-70 volumetric percentage to be applied into the vials with 70%-ethanol and sterilized with ionizing radiation at the dosage of 1.5 Mrad.

EFFECT: higher efficiency.

3 ex

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RU 2 281 061 C1

Authors

Bagrov Sergej Nikolaevich

Ronkina Tamara Il'Inichna

Malyshev Vladimir Borisovich

Petrenko Aleksandr Egorovich

Dates

2006-08-10Published

2005-02-15Filed