FIELD: organic chemistry.
SUBSTANCE: invention relates to method for production of 4-(ω-hydroxyalkyloxy)-4'-cyanobyphenyls by reaction of 4-hydroxy-4'-cyanobyphenyl with ω-chloro-1-alkanols under heating. Reaction is carried out in boiling dimethylformamide medium in presence of potash for 2-4 h in the next molar ratio: (4-hydroxy-4'-cyanobyphenyl):(ω-chloro-1-alkanol):(potash) = 1:(1-1.2):(1-1.2).
EFFECT: accelerated, simplified method of decreased cots; increased yield of target product.
1 tbl, 1 ex
| Title |
Year |
Author |
Number |
| METHOD OF PRODUCING 4-[(2,3-EPOXYPROPOXY)ALKYLOXY]-4'-CYANOAZOBENZENES |
2012 |
- Potemkina Ol'Ga Vladimirovna
- Kuvshinova Sof'Ja Aleksandrovna
- Kojfman Oskar Iosifovich
|
RU2493151C1 |
| METHOD OF PRODUCING PIPERIDINE DERIVATIVES OR SALTS THEREOF |
0 |
- Karl Shenker
- Rajmond Bernaskoni
|
SU679136A3 |
| 4-(4-CYANOPHENYL)-4'-(4-HYDROXYHEXYLOXY)-BENZYLIDENANILINE, SHOWING PROPERTIES OF LIQUID CRISTALLINE STATIONARY PHASE FOR GAS CHROMATOGRAPHY |
2007 |
- Kuvshinova Sof'Ja Aleksandrovna
- Burmistrov Vladimir Aleksandrovich
- Fokin Denis Sergeevich
- Kojfman Oskar Iosifovich
- Blokhina Svetlana Vital'Evna
- Ol'Khovich Marina Vasil'Evna
- Sharapova Anzhelika Valer'Evna
|
RU2339616C1 |
| METHOD OF PRODUCING DERIVATIVES OF 6-PHENYL-S-TRIAZOLO/4,3-A/PYRIDO/2,3-F/-1,4-DIAZEPINES |
0 |
- Valter Fon Bebenburg
- Norbert Shulmajer
- Vladimir Yakovlev
|
SU667137A3 |
| METHOD OF PREPARING 3,4-DIHYDROCARBOSTYRENE DERIVATIVES OR SALTS THEREOF |
0 |
- Katsuyuki Nakagava
- Nanami Murakami
- Siro Esizaki
- Khideo Mori
- Mitiaki Tominaga
- Yasumitsu Tamura
|
SU580835A3 |
| 2-SACCHARINYLMETHYL(ARYL OR ARYLHYDROXY) ACETATES, OR THEIR SALTS FORMED BY ADDITION OF ACIDS TO THESE BASIC COMPOUNDS, OR THEIR SALTS FORMED BY BASES ADDITION TO THESE ACID COMPOUNDS, AND PHARMACEUTICAL COMPOSITION INHIBITING ACTIVITY OF PROTEOLYTIC ENZYMES |
1992 |
- Li Gamil'Ton Lehjtimer[Us]
- Richard Pol' Danlehp[Us]
|
RU2081871C1 |
| L-(-)-2-(AMINOCARBONYL)-N-(4-AMINO-2,6-DICHLOROPHENYL)-4-[5,5- -BIS-(4-FLUOROPHENYL)-PENTYL]-1-PIPERAZINE ACETAMIDE, ITS PHARMACEUTICALLY ACCEPTABLE SALT OR HYDRATE, A METHOD OF ITS SYNTHESIS AND AN AGENT FOR DONOR HEART STORAGE |
1990 |
- Kherman Van Belle[Be]
- Villi Dzhon Karolus Van Laerkhoven[Be]
|
RU2093156C1 |
| 2-(4-HYDROXYPIPERIDINO)-1-ALKANOL DERIVATIVES AND 2-(4- HYDROXYPIPERIDINO)-1-ALKANONE DERIVATIVES |
1992 |
|
RU2065859C1 |
|
0 |
- Kuppusvamy Nagarayan
- Vishva Prakash Aria
- Tomas George
|
SU542473A3 |
| 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES |
2005 |
- Kato Masaja
- Sato Norifumi
- Okada Minoru
- Uno Tetsujuki
- Ito Nobuaki
- Takedzi Jasukhiro
- Sinokhara Khisasi
- Fuva Masakhiro
|
RU2386628C2 |
