FIELD: medicine, as agents for medical treatment of traumatic brain injuries. SUBSTANCE: product: 2-(4- hydroxypiperidino)-1-alkanol derivatives of formula 1 wherein R2 is H or CH3, M and Q form divalent radical Z which is selected from groups of formula 2,3 and 4. Reagent 1: compound of formula 5 wherein R2,, M and Q are as defined above. Reagent 2: sodium borohydride. Reaction conditions: in protic solvent at 15-25 C. Structure of compounds of formulae 1,2,3,4 and 5 (, , , , ). EFFECT: improved properties of the title compounds. 8 cl
Authors
Dates
1996-08-27—Published
1992-06-19—Filed