PEPTIDE COMPOUNDS Russian patent published in 2006 - IPC C07K5/78 C07K5/06 A61K38/05 A61P37/06

Abstract RU 2281955 C2

FIELD: chemistry of peptides, medicine, pharmacy.

SUBSTANCE: invention relates to compound of the formula (I): wherein R¹ represents benzofuranyl substituted with halogen atom or styryl substituted with halogen atom; R² represents substituted hydroxyl substituted with mercapto-group or substituted sulfonyl, or its pharmaceutically acceptable salts. Compound of the formula (I) and its pharmaceutically acceptable salts possess the strong inhibitory effect on production of nitrogen oxide (NO) and can be useful in prophylaxis and/or treatment of NO-mediated diseases in humans and animals.

EFFECT: valuable medicinal and biochemical properties of compounds.

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RU 2 281 955 C2

Authors

Sima Itiro

Okhkava Takekhiko

Sato Kentaro

Isibasi Naoki

Imamura Kenitiro

Dates

2006-08-20—Published

2001-12-18—Filed