NEW APPLICATION OF COMBINED SELECTIVE ANTAGONISTS OF DOPAMINE D2 RECEPTOR AND AGONISTS OF 5-НТ RECEPTOR Russian patent published in 2006 - IPC A61K31/4433 A61K31/275 A61P25/22 A61P25/18 A61P43/00

Abstract RU 2283648 C2

FIELD: veterinary medicine and veterinary pharmacology.

SUBSTANCE: invention relates to application of compounds combining properties of selective antagonists of dopamine D2 receptor and agonists of 5-HT_1A receptor, in particular (R)-(-)-2-[5-(4-fluorophenyl)-3-piridylmethylaminomethyl]-chromane or pharmaceutically acceptable salts thereof, or N-(4'-fluoro-3-biphenylmethyl)-N-2-(3-cyanophenoxyethyl)-amine or pharmaceutically acceptable salts thereof. Said compounds are useful in veterinary medicine for treatment of self-directed traumatic disorders, associated with behavioral stress-factors, and/or compulsive disorders, associated with behavioral stress-factors, and/or anxiety, associated with behavioral stress-factors.

EFFECT: effective method for treatment and prophylaxis of disorders, associated with behavioral stress-factors.

6 cl, 3 ex

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RU 2 283 648 C2

Authors

Bartoshik Gerd

Dates

2006-09-20—Published

2001-10-25—Filed