FIELD: medicine.
SUBSTANCE: the present innovation deals with treating diseases associated with affected tissue circulation. It deals with injecting mononuclear cells of donor's umbilical cord blood into the blood. Moreover, the above-mentioned donor's cells have got the set of antigens HLA-A, HLA-B, HLA-DR being distinct against the recipient's set of antigens HLA-A, HLA-B, HLA-DR by not less than four antigens. The quantity of introduced cells ranges 2.5 x 106 up to 10 x 106/kg body weight/d. Injection should be repeated 2-10 times at interval of 10-60 d. The innovation provides substitution of dead and/or recipient's regeneration-impotent cells with the above-mentioned donor's cells and enables to decrease the frequency of immunopathological reactions at decreasing the number of introduced donor's mononuclear cells.
EFFECT: higher efficiency of therapy.
2 cl, 8 ex, 1 tbl
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METHOD FOR TREATMENT OF GENERALIZED INFECTIONS MORDIBIDIZED BY BACTERIA OR FUNGI AND PROTOZOA, OR ARTERIOSCLEROSIS, OR DIABETES MELLITUS, OR DISEASES MEDIATED BY DELAYED HYPERRESPONSIVENESS REACTION, OR DISEASES MEDIATED BY SOMATIC CELL GENE MUTATIONS | 2004 |
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Authors
Dates
2006-09-27—Published
2005-06-14—Filed