METHOD FOR TREATING ISCHEMIC CARDIAC DISEASE, OR MYOCARDIAL INFARCTION AND ITS AFTEREFFECTS, OR CEREBRAL ISCHEMIA INDUCED BY ATHEROSCLEROSIS OR ACUTE DYSFUNCTION OF CEREBRAL CIRCULATION, AND ITS AFTEREFFECTS, OR ATHEROSCLEROSIS-INDUCED ISCHEMIA OF INFERIOR LIMBS Russian patent published in 2006 - IPC A61K35/14 A61P9/10 

Abstract RU 2284190 C1

FIELD: medicine.

SUBSTANCE: the present innovation deals with treating diseases associated with affected tissue circulation. It deals with injecting mononuclear cells of donor's umbilical cord blood into the blood. Moreover, the above-mentioned donor's cells have got the set of antigens HLA-A, HLA-B, HLA-DR being distinct against the recipient's set of antigens HLA-A, HLA-B, HLA-DR by not less than four antigens. The quantity of introduced cells ranges 2.5 x 106 up to 10 x 106/kg body weight/d. Injection should be repeated 2-10 times at interval of 10-60 d. The innovation provides substitution of dead and/or recipient's regeneration-impotent cells with the above-mentioned donor's cells and enables to decrease the frequency of immunopathological reactions at decreasing the number of introduced donor's mononuclear cells.

EFFECT: higher efficiency of therapy.

2 cl, 8 ex, 1 tbl

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RU 2 284 190 C1

Authors

Genkin Dmitrij Dmitrievich

Surkov Kirill Gennadievich

Dates

2006-09-27Published

2005-06-14Filed