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(19)

RU

(11)

2 285 525

(13)

C2

(51)

IPC

A61K31/385(2006-01-01)

A61K31/401(2006-01-01)

A61K31/403(2006-01-01)

A61K31/137(2006-01-01)

A61P13/12(2006-01-01)

(21) (22)

Application

2003137772/15, 2002-05-24

(24)

Start date

2002-05-24

(22)

Actual filing date

2002-05-24

(45)

Published

2006-10-20

(72)

Inventor

Teger Mikhel'Anzorge ZigfridFris GerkhardKoegst Diter

(73)

Holder

Zerumverk Bernburg Ag

MEDICINAL AGENT COMPRISING GLUTATHIONE METABOLISM EFFECTOR ALONG WITH α-LIPOIC ACID FOR THERAPY IN KIDNEY TRANSPLANTATION Russian patent published in 2006 - IPC A61K31/385 A61K31/401 A61K31/403 A61K31/137 A61P13/12 

Abstract RU 2285525 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to a combined medicinal preparation used in treatment of disturbance of thiol-disulfide status in kidney transplantation that comprises ambroxol as an effector of glutathione metabolism, α-lipoic acid and additives. Also, invention relates to using inhibitors of activity of angiotensin-converting enzyme - kaptopril, enalapril and ramipril or ambroxol along with α-lipoic acid for preparing a medicinal agent used in treatment of disturbance of thiol-disulfide status in kidney transplantation. Invention provides enhancing effectiveness of treatment.

EFFECT: valuable medicinal property of agent and its enhanced effectiveness.

14 cl, 7 dwg, 7 tbl, 6 ex

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RU 2 285 525 C2

Authors

Teger Mikhel'

Anzorge Zigfrid

Fris Gerkhard

Koegst Diter

Dates

2006-10-20—Published

2002-05-24—Filed

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