FIELD: organic chemistry, medicine.
SUBSTANCE: invention relates to derivatives of sulfamide of the general formula (I):
or their pharmaceutically acceptable salts, enantiomers, diastereoisomers or their mixtures wherein R1 means C6-aryl optionally substituted with 1-3 groups of Ra wherein Ra mean halogen atom; R means (C1-C8)-alkyl that can be substituted with cycloalkyl, C6-heterocycloalkyl comprising oxygen atom as a heteroatom, (C1-C6)-alkoxy-group, Compounds can be used in preparing a medicinal agent for inhibition of Bacillus anthracis lethal factor activity. Also, invention describes a pharmaceutical composition based on compounds of the formula (I) and using these compounds.
EFFECT: valuable medicinal properties of compounds.
7 cl, 1 tbl, 146 ex
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