SELECTIVE GLYCOSIDASE INHIBITORS AND USE THEREOF Russian patent published in 2017 - IPC C07H9/06 C07D513/04 A61K31/7056 A61K31/429 A61P25/00 A61P25/28 A61P35/00 A61P43/00 

Abstract RU 2609210 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formulae (1), (2) or (3), or pharmaceutically acceptable salt thereof. Invention also relates to a pharmaceutical composition containing as an active ingredient a compound of formulae (1), (2) or (3), having inhibitory action on O-GlcNAcase, or a pharmaceutically acceptable salt thereof and pharmaceutically acceptable carrier. Compounds or pharmaceutically acceptable salt thereof are intended for treating Alzheimer's disease, Parkinson's disease or progressive supranuclear palsy (PSP) in a human patient in need thereof.

EFFECT: technical result is compounds which are selective inhibitors of glycosidase.

45 cl, 6 tbl, 33 ex

(1), (2),

(3).

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RU 2 609 210 C2

Authors

Kaul Ramesh

Makichern Ernest Dzh.

Mu Chanvej

Selnik Garold G.

Vokadlo Devid Dzh.

Van Yaode

Vej Chzhunyun

Chzhou Yuansi

Chzhu Yunbao

Dates

2017-01-31Published

2011-12-21Filed