FIELD: organic chemistry, medicine, immunology, pharmacy.
SUBSTANCE: invention relates to novel immune active aminoalkylglucosaminide phosphate compounds of the formula (V):
or its pharmaceutically acceptable salts wherein X is chosen from the group consisting of -O- and -NH-; R1, R2 and R3 are chosen independently of one another from the group consisting of (C9-C14)-acyl groups. Also, invention relates to the immunostimulating pharmaceutical composition comprising pharmaceutically acceptable carrier and the therapeutically effective dose of compound of the formula (V), and to a method for inducing the immune response in a patient.
EFFECT: improved inducing response method, valuable medicinal properties of compounds and pharmaceutical composition.
19 cl, 4 tbl, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PREVENTIVE AND THERAPEUTIC METHOD FOR TREATING INFECTIOUS AND OTHER DISEASES BY APPLYING IMMUNOEFFECTIVE COMPOUNDS | 2002 |
|
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| SYNTHETIC GLUCOPYRANOSYLLIPID ADJUVANTS | 2010 |
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| SYNTHETIC GLUCOPYRANOSYL LIPOID ADJUVANTS | 2010 |
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| CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPAHTE DERIVATIVES AND USE THEREOF | 2004 |
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| USE OF MONOMYCOLYL GLYCEROL (MMG) AS ADJUVANT | 2008 |
|
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| METHODS OF OBTAINING AMINOALKYLGLUCOSAMINIDPHOSPHATES AND DISACCHARIDE IMMUNOEFFECTORS AND THEIR INTERMEDIATE COMPOUNDS | 2003 |
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| NEW ADJUVANT COMPOSITIONS | 2009 |
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