COMPOSITION CONTAINING TLR AGONIST AND METHODS FOR ITS APPLICATION Russian patent published in 2021 - IPC C07K14/705 A61K33/06 A61K35/74 A61K35/76 A61K39/00 A61K39/02 A61K39/12 

Abstract RU 2761870 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology. A group of inventions is described, including a composition for enhancing the adsorption of a TLR agonist on aluminum salts, a method for stimulating an immune response in a subject, and a method for obtaining a composition for stimulating an immune response in a subject containing a TLR agonist selected from a TLR7/8 agonist or a TLR4 agonist, and an auxiliary lipid. In one of the embodiments, the composition contains a TLR agonist selected from a TLR7/8 or TLR4 agonist, an auxiliary lipid, and an aluminum salt.

EFFECT: invention expands the arsenal of means for stimulating the immune response in a subject with enhanced adsorption of the TLR agonist on aluminum salts.

25 cl, 28 dwg, 4 tbl, 2 ex

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RU 2 761 870 C2

Authors

Foks Kristofer B.

Dates

2021-12-13Published

2017-05-11Filed