FIELD: medicine, pharmaceutics.
SUBSTANCE: invention concerns microbiology and immunology. An adjuvant composition of 3-O-deacylated 4'-monophosphoryl lipid A (3D-MLA), contains at least 20 mole % of hexa-acyl version which is extracted from Salmonella bacteria, particularly Salmonella minnesota R595.
EFFECT: use of the declared composition allows preserving or increasing immunopotentiating properties and lowering toxicity.
6 cl, 6 ex, 3 tbl, 1 dwg
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|
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|
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|
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|
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|
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- Aparin P.G.
- L'Vov V.L.
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- Golovina M.Eh.
- Shmigol' V.I.
|
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