FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, and may be used for preparing an adjuvant or an immune-stimulating agent. That is ensured by the use of synthetic monomycolyl glycerol (MMG) based on the alkyl chains of 8-36 carbon atoms. Most preferentially, the alkyl chain of 8-16 carbon atoms. There are also provided an adjuvant for enhancing the immune response, an immunomodulator for stimulating the dendritic cells, synthetic MMG, a vaccine and a delivery system.
EFFECT: group of inventions provides stimulation and activation of the human dendritic cells (DCs) in the low dose that is effective in treating cancer, autoimmune disorders, neurvous disorders, such as Alzheimer's disease, airway inflammation, and infectious diseases, skin disorders, allergies or asthma.
19 cl, 12 dwg, 1 tbl, 10 ex
| Title | Year | Author | Number |
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| COMPOSITION FOR STIMULATING DENDRITIC CELL MATURATION, CONTAINING HYBRID PROTEIN RV2299C/ESAT-6 | 2017 |
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| MULTI-EPITOPE POLYPEPTIDE FOR IMMUNIZATION AGAINST MYCOBACTERIUM TUBERCULOSIS | 2023 |
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|
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| IMMUNOLOGICAL ADJUVANT BASED ON NANOPARTICLES FOR VACCINES AGAINST HIGHLY PATHOGENIC INFLUENZA VIRUSES STRAINS | 2013 |
|
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| COMPLEX CONTAINING AN OLIGONUCLEOTIDE, HAVING IMMUNOSTIMULATING ACTIVITY, AND ITS APPLICATION | 2014 |
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| VACCINE COMPOSITIONS WITH CATION LIPIDES AND METHODS OF APPLICATION | 2013 |
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