FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention relates to a method for synthesis of 1-[3-hydroxy-3-(pyrid-4-yl)prop-1-yl]-1,2-dihydro[60]fullerene. Method involves interaction of C60 with triethylaluminum in the presence of catalyst, in argon atmosphere, at room temperature and under atmosphere pressure, in toluene medium for 8 h followed by addition of nickel-containing catalyst and 4-pyridinecarbaldehyde at temperature -15°C followed by stirring the reaction mass at room temperature for 6-10 h and the following hydrolysis. The total yield of end substances after hydrolysis of the reaction mass is 48-69%. Proposed compounds can be used in fine organic synthesis, in manufacture of drugs and biologically active substances. Invention provides the development of method for synthesis of novel fullerene-containing alcohols.
EFFECT: improved method of synthesis.
1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREPARING 1-[3-HYDROXY-3-ARYLPROP-1-YL]-1,2-DIHYDRO[60]FULLERENES | 2005 |
|
RU2290367C1 |
| METHOD FOR PREPARING 1-[1-HYDROXY-1-(PYRID-4-YL)METHYL]-1,2-DIHYDRO[60]FULLERENES | 2005 |
|
RU2294928C2 |
| METHOD FOR PREPARING 1-[3-HYDROXY-4-(FUR-2-YL)PROP-1-YL]-1,2-DIHYDRO[60]FULLERENES | 2005 |
|
RU2290401C1 |
| METHOD FOR PREPARING 1-[3'-HYDROXY-3'-ALKYL-(3',3'-DIALKYL)]-N-PROPYL-2-HYDRO[60]FULLERENES | 2003 |
|
RU2238929C1 |
| METHOD FOR PRODUCTION OF 1-HYDROXY-2,3-[60]FULLEROCYCLOPENTANECARBOXYLIC ACID ETHYL ESTER | 2005 |
|
RU2283830C1 |
| METHOD FOR PRODUCTION OF 1-ETHENYL-1-METHYL-1-SILA-2,3-[60]FULLEROCYCLOPENTANE | 2005 |
|
RU2283844C1 |
| METHOD FOR PREPARING 1-(3',3'-DIALKOXYPROP-1'-YL)-2-HYDRO[60]FULLERENES | 2003 |
|
RU2238930C1 |
| METHOD FOR PREPARING 1-[1'-HYDROXY-1'-ALKYL-(1',1'-DIALKYL)]-METHYL-2-HYDRO[60]FULLERENES | 2003 |
|
RU2238263C1 |
| METHOD FOR PREPARING 1-ETHYL-3,3-DIALKYL-6,7-FULLERENO[60]CYCLOHEPTA-2-OX-1-ALANES | 2002 |
|
RU2206570C1 |
| METHOD OF SYNTHESIS OF 1-ETHYL-2,3-FULLERENEALUMINOCYCLO- -PENTANES | 1997 |
|
RU2132332C1 |
