FIELD: medicine, molecular-biological researches, oncodiagnostics.
SUBSTANCE: the declared method and multi-purpose diagnostic kit (DK) are indicated for carrying out medico-genetic analysis of simultaneously several mutations (polymorphisms) of different genes, those associated with some frequent multifactorial diseases, among them. Due to applying standard component of the mixture and standard oligoprimers, optimizing the conditions for performing polymerase chain reaction (PCR) and analyzing polymorphism of restriction fragments length (PRFL) the rate of such an analysis has been shortened up to 2-3 d. The innovation simplifies and cheapens the analysis in question and makes it useful for carrying out molecular investigations both in specialized centers and in multi-purpose laboratories.
EFFECT: higher accuracy and efficiency of detection.
2 cl, 2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING CARDIO-VASCULAR DISEASES AND DIAGNOSTIC KIT FOR ITS IMPLEMENTATION | 2005 |
|
RU2304775C2 |
| METHOD OF DETERMINING PHYSICAL CAPABILITY OF HUMAN BEING | 2008 |
|
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| METHOD OF GENETIC POLYMORPHISM ANALYSIS FOR CARRYING OUT POSTNATAL DNA-DIAGNOSTICS OF MUCOVISCIDOSIS | 2008 |
|
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| METHOD FOR GENETIC MARKER PREDICTION OF RISK OF GESTOSIS | 2010 |
|
RU2431842C1 |
| METHOD FOR PREDICTION OF HUMAN BODY LENGTH BY DNA ANALYSIS WITHIN RUSSIAN POPULATION | 2012 |
|
RU2531341C2 |
| KIT WITH LYOPHILISED PRIMERS FOR PCR DIAGNOSIS OF FOETAL RHESUS FACTOR GENE BY PREGNANT WOMAN'S BLOOD | 2014 |
|
RU2576780C2 |
| METHOD AND SET OF REAGENTS FOR DETECTION OF POLYMORPHISMS IN LINGO1, LINGO2 AND SLC1A2 GENES, DETERMINING GENETIC ASSOCIATION WITH ESSENTIAL TREMOR | 2015 |
|
RU2631615C2 |
| METHOD OF DETERMINING PREDISPOSITION TO LONG PHYSICAL EFFORT | 2011 |
|
RU2468086C1 |
| METHOD OF ESTIMATING RISK OF METABOLIC SYNDROME DEVELOPMENT IN CHILDREN BASING ON GENETIC AND BIOCHEMICAL MARKERS | 2012 |
|
RU2492485C1 |
| METHOD FOR PREDICTING THE DEVELOPMENT OF TOXIC HEPATITIS AT CHEMOTHERAPY OF MULTIPLE MYELOMA | 2005 |
|
RU2283494C1 |
