FIELD: biotechnology.
SUBSTANCE: method and a set of reagents are proposed for detection of genetic polymorphism at polymorphic points rs9652490 LINGO1 (A>G), rs11856808 LINGO1 (C>T), rs10968280 LINGO2 (C>T), rs7033345 LINGO2 (C>T), rs1412229 LINGO2 (A>T), rs10812774 LINGO2 (C>T) and rs3794087 SLC1A2 (A>C), which determine genetic association with the essential tremor.
EFFECT: high specificity and shortening of the identification of oligonucleotide polymorphisms due to the possibility to estimate seven single nucleotide polymorphic markers in a multiplex format in one formulation.
3 cl, 21 dwg, 19 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| KIT OF REAGENTS FOR DETECTION AND IDENTIFICATION OF DNA OF BRUCELLOSIS AGENTS BY REAL-TIME POLYMERASE CHAIN REACTION OM-SCREEN-BRUCELLOSIS-RV | 2018 |
|
RU2715333C1 |
| METHOD FOR DETECTING SPECIFIC NUCLEOTIDE SEQUENCES AND NUCLEOTIDE REPLACEMENTS BY REAL-TIME PCR WITH EFFECT OF PROBE FLUORESCENCE QUENCHING SHOWN BY PRIMER | 2010 |
|
RU2451086C1 |
| SET AND METHOD FOR ACCELERATED PLAGUE MICROBE IDENTIFICATION AND SIMULTANEOUS DIFFERENTIATION OF VIRULENT AND AVIRULENT STRAINS OF YPESTIS BY PLASMID PROFILING THEREOF | 2011 |
|
RU2473701C1 |
| METHOD FOR DIAGNOSING VARIANT SOPH c.5741G>A IN NBAS GENE | 2024 |
|
RU2819985C1 |
| METHOD FOR GENOTYPING POLYMORPHIC LOCUS rs7986407 (A>G) OF FOXO1 GENE IN HUMAN BY REAL-TIME PCR USING ALLELE-SPECIFIC FLUORESCENT PROBES | 2024 |
|
RU2826734C1 |
| KIT FOR DETERMINING THE ABUNDANCE OF THE APP GENE IN THE HUMAN GENOME | 2021 |
|
RU2789799C1 |
| KIT FOR DETERMINING CCR5DELTA32 MUTATIONS IN HUMAN GENOME | 2020 |
|
RU2748998C1 |
| SET OF OLIGONUCLEOTIDE PRIMERS AND FLUORESCENT-LABELLED PROBES AND METHOD FOR DETECTING DNA OF AGENTS OF GLANDERS AND MELIOIDOSIS BY PCR METHOD WITH PRODUCT DETECTION IN REAL TIME | 2019 |
|
RU2738358C1 |
| METHOD FOR GENOTYPING POLYMORPHIC LOCUS rs11024031 (TC) OF THE C11orf58 GENE IN HUMANS BY REAL-TIME PCR USING ALLELE-SPECIFIC FLUORESCENT PROBES | 2023 |
|
RU2819931C1 |
| TEST SYSTEM FOR DETECTING SARS-CoV-2, INFLUENZA VIRUS A, INFLUENZA VIRUS B BY THE METHOD OF ONE-STEP POLYMERASE CHAIN REACTION WITH REVERSE TRANSCRIPTION | 2021 |
|
RU2761481C1 |
