FIELD: biotechnology.
SUBSTANCE: method and a set of reagents are proposed for detection of genetic polymorphism at polymorphic points rs9652490 LINGO1 (A>G), rs11856808 LINGO1 (C>T), rs10968280 LINGO2 (C>T), rs7033345 LINGO2 (C>T), rs1412229 LINGO2 (A>T), rs10812774 LINGO2 (C>T) and rs3794087 SLC1A2 (A>C), which determine genetic association with the essential tremor.
EFFECT: high specificity and shortening of the identification of oligonucleotide polymorphisms due to the possibility to estimate seven single nucleotide polymorphic markers in a multiplex format in one formulation.
3 cl, 21 dwg, 19 tbl, 1 ex
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