FIELD: medical diagnostics.
SUBSTANCE: invention relates to reagent kit for revealing brain condition in mammals, in particular for diagnosing drug addiction. Proposed reagent kit contains antibodies for two epitopes (MDOR) of peptide fragment of recombinant opiate mu/delta receptor: chicken IgYs obtained against synthetic MDOR peptide immobilized on solid polymeric carrier, polyclonal human IgGs containing MDOR antibodies immobilized on polymeric carrier, and reagents for determining MDOR peptide conjugated with fluorescein, colloidal gold, horse-radish peroxidase, polyclonal human IgGs containing MDOR antibodies and conjugated with fluorescein, colloidal gold, horse-radish peroxidase, and goat antibodies obtained against chicken IgYs.
EFFECT: enhanced sensitivity of method.
10 cl, 6 dwg, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| TEST SYSTEM FOR DETECTING OPIUM NARCOMANIA | 2001 |
|
RU2193199C1 |
| PREDICTING THE COURSE AND OUTCOME OF COMA AND POST-COMA UNCONSCIOUS STATES (INCLUDING VEGETATIVE ONES) WITH THE HELP OF BLOOD TESTS | 2016 |
|
RU2648515C1 |
| DIAGNOSTIC CIS-TEST SET OF REAGENTS FOR CHECKING CEREBRAL ISCHEMIA OF MAMMALIANS | 1998 |
|
RU2146826C1 |
| TEST SET FOR DIAGNOSING NEUROLOGIC DISEASES | 1995 |
|
RU2112243C1 |
| DIAGNOSTIC KIT OF REAGENTS FOR DETECTING CHRONIC PATHOLOGIES OF THE BRAIN OF ISCHEMIC GENESIS | 2017 |
|
RU2668534C1 |
| METHOD OF DIAGNOSING ACUTE CEREBRAL ISCHEMIA | 1996 |
|
RU2123704C1 |
| BIOMARKERS OF ISCHEMIA AND THEIR APPLICATION FOR PREDICTION OF UNFAVOURABLE NEUROLOGIC CONSEQUENCES OF SURGICAL OPERATION | 2006 |
|
RU2435165C2 |
| KIT OF REAGENTS FOR IMMUNE-ENZYME ASSAY OF ENDOGENOUS BIOREGULATOR ANTIBODIES IN BLOOD SERUM FOR DETECTING ADDICTION DISORDERS | 2011 |
|
RU2495433C2 |
| METHOD OF DIAGNOSTICS OF SOMATO-ALLERGIC REACTION DEVELOPMENT RISK ASSOCIATED WITH COMNSUMPTION OF SPECIAL BABY FOOD STUFF (SBFS) BY MEANS OF TEST-SYSTEM "LACTEST" | 2006 |
|
RU2327166C2 |
| IMMUNOENZYME TEST SYSTEM FOR DETERMINATION OF PERTUSSIS ANTIBODIES IN HUMAN AND ANIMAL BLOOD SERUM | 2015 |
|
RU2582959C1 |
