DERIVATIVE OF 5-METHOXY-8-ARYL[1,2,4]-TRIAZOLE[1,5-a]PYRIDINE Russian patent published in 2007 - IPC C07D471/04 A61K31/437 A61P25/16 A61P25/28 

Abstract RU 2298009 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention describes a novel derivative of 5-methoxy-8-aryl[1,2,4]-triazole[1,5-a]pyridine of the general formula (I): wherein R1 means hydrogen, halogen atom or lower alkoxy-group; R2 means -C(O)-phenyl wherein ring can be unsubstituted or substituted with one or two substitutes chosen from group consisting of halogen atom, lower alkyl, lower alkoxy-group or trifluoromethyl, or it means -C(O)-furanyl or -C(O)-thiophenyl wherein rings are not substituted or substituted with halogen atom, and its pharmaceutically acceptable salts. Proposed compounds can be used in treatment of diseases associated with adenosine A2 receptors. Also, invention describes a medicinal agent used in treatment of diseases associated with adenosine A2A receptors containing compound of the formula (I) and pharmaceutically acceptable excipients.

EFFECT: valuable medicinal properties of agent.

8 cl, 1 tbl, 1 ex

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RU 2 298 009 C2

Authors

Nettekoven Genrikh Mattias

Shmitt Sebast'En

Dates

2007-04-27Published

2002-09-28Filed