FIELD: microbiology.
SUBSTANCE: method involves carrying out morphological investigations using morphometric evaluation of preparation quality by its harmless and effectiveness of topical protective response based on state of three groups of cellular fractions of intestine mucosa comprising interepithelial lymphocytes, apudocytes and goblet-shaped cells. Material is sampled from three compartments of intestine: duodenum, ileum and ascending region of colon. Obtained quantitative data are subjected for mathematical treatment using developed coefficients and indices calculated by formulae. Advantage of invention involves expanding assortment of evaluating criteria. Invention is directed for enhancing evaluation of quality of vaccine preparations used against cholera.
EFFECT: improved and valuable evaluating method.
4 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| AVIRULENT STRAIN OF BACTERIA Vibrio cholerae BIOVAR eltor, SEROVAR Ogava (ctxA-, tcpA-, toxR-, zot-), USED IN IMMUNOLOGICAL AND GENETIC INVESTIGATIONS AND EDUCATORY PROCESS | 2004 |
|
RU2254371C1 |
| AGENT FOR DISBACTERIOSIS TREATMENT AND PROPHYLAXIS | 1994 |
|
RU2071339C1 |
| METHOD FOR PREDICTING CHRONIC ISCHEMIA OF LARGE INTESTINE AT ATHEROSCLEROTIC LESION OF INFERIOR MESENTERIC ARTERY | 2002 |
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RU2221480C2 |
| STRAIN OF MICROORGANISM ESCHERICHIA COLI KM 148 AS PRODUCER OF PROTECTIVE ANTIGENS USED FOR IMMUNOPROPHYLAXIS OF COLI-BACTERIOSIS AND CHOLERA | 2002 |
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| STRAIN OF BACTERIUM VIBRIO CHOLERAE KM-168 AS BASE FOR CONSTRUCTION OF LIVE VACCINE AGAINST DIARRHEA DISEASE CAUSED BY PATHOGENIC STRAINS OF VIBRIO CHOLERAE O139 | 2003 |
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| METHOD OF GEE'S DISEASE DIAGNOSTICS | 2007 |
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RU2333491C1 |
| METHOD OF PREPARING OF VACCINE AGAINST CHOLERA | 1991 |
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RU2021816C1 |
| METHOD OF EARLY DIAGNOSTICS OF CHRONIC ISCHEMIA OF LARGE INTESTINE IN CASE OF ATHEROSCLEROTIC LESION OF INFERIOR MESENTERIC ARTERY | 2008 |
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