FIELD: organic chemistry.
SUBSTANCE: invention relates to 4-amino-5-phenyl-7-cyclobutylpyrrolo[2,3-d]pyrimidine derivatives of general formula I wherein meanings of R1, R2, R4, and X are as described in the disclosure, and salts thereof. Said derivatives are capable to inhibit IGR-IR tyrosin kinase activity and are useful in production of pharmaceutical composition for treatment of proliferative decisions. Pharmaceutical composition based on abovementioned derivatives and method for production thereof also are disclosed.
EFFECT: new derivatives for treatment of proliferative decisions.
9 cl, 134 ex
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Authors
Dates
2007-09-10—Published
2002-05-13—Filed