FIELD: virology, immunology.
SUBSTANCE: vaccine strain is obtained by cross-breed of specific epidemic virus with cold-adapted temperature-sensitive virus as attenuation donor. Strain actively multiplies in developing hen embryos at optimal temperature of 33°C and is characterized with cold-adaptation and temperature-sensitivity. Strain has genes from epidemic virus encoding hemagglutinin and neuraminidase and six genes from attenuation donor encoding non-glycosilated proteins.
EFFECT: new strain for living influenza intranasal vaccine for infants and adults.
1 tbl
| Title | Year | Author | Number |
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| STRAIN OF VIRUS OF FLU A/17/WISCONSIN/05/84 (H3N2) FOR MANUFACTURE OF LIVE INFLUENZAL INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2007 |
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| FIELD: medicinal virology | 1996 |
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| STRAIN A/17/NANCHANG/95/4 (H3N2) FOR PRODUCTION OF LIVING AN ANTIINFLUENZA INTRANASAL VACCINE FOR ADULTS | 1997 |
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| STRAIN A/47/NANCHANG/95/13 (H3N2) FOR PRODUCTION OF LIVE ANTIINFLUENZA INTRANASAL VACCINE FOR CHILDREN | 1997 |
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