FIELD: organic chemistry.
SUBSTANCE: invention relates to improved method for production of 3-aminopyperidine derivatives of formula Ib useful in production of protein kinases, wherein R1 is C1-C6-alkyl; R2 is hydrogen, C1-C6-alkyl; R3 is hydrogen, C1-C6-alkyl; R13 is phenyl; n = 1-4. Said method includes reduction of compound of formula II, , wherein R14 is C1-C6-alkyl with reducing agent.
EFFECT: improved method for production of 3-aminopyperidine derivatives.
7 cl, 3 dwg, 2 ex
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Authors
Dates
2007-10-27—Published
2003-11-10—Filed