FIELD: organic chemistry.
SUBSTANCE: described is 3-phenylsulfonyl-8-piperazin-1-yl-quinoline of formula I 
or pharmaceutically acceptable salt thereof, wherein R1 and R2 are independently hydrogen or C1-C6-alkyl, or R1 and R2 together form group (CH2)2, (CH2)3 or (CH2)4; R3, R4 and R5 are hydrogen, halogen or C1-C6-alkyl; m = 1-4; n = 1-3; A is -Ar1, Ar1 is optionally substituted with 1 or more substituents. Disclosed are four methods for production of abovementioned compounds.
EFFECT: new compounds with affinity to 5-HT6 receptor.
23 cl, 5 tbl, 52 ex, 6 dwg
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