METHOD OF TREATING EYELID MALIGNANCIES Russian patent published in 2012 - IPC A61K31/196 A61K31/573 A61K35/16 A61P35/00 A61N5/10 A61B17/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, oncology, and can be used for combination treatment of the patients suffering eyelid malignancies. A method involves local radiomodification by peritumoral introduction of Methotrexate 10 mg pre-incubated in autoplasma 10 ml at t=37°C for 30 minutes preceded by subbulbar introduction of diprospan 1 ml. One hour later, the radiomodification is followed by neoadjuvant radiation therapy at depth 0.5 cm by basic dose 20 Gy, and no more than 24 hours after the radiation, a surgical operation is performed.

EFFECT: method provides intensified radicality of the tumour exposure, higher surgical ablasticity, lower risk of cancer dissemination, maximally maintained reparation ability and functions of normal ocular tissues, minimised therapeutic complications, reduced length of treatment.

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