DERIVATIVES OF 3-HYDROXY-2-PYRIDONE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 2008 - IPC C07D213/89 C07D401/06 C07D401/14 C07D417/06 A61K31/4412 A61K31/4427 A61P31/04

Abstract RU 2321584 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to derivatives of 3-hydrozy-2-pyridone represented by the formula (I): wherein R₁ means aryl optionally substituted with one or more alkyl group; R₂means hydrogen atom; each R₃ and R₄ is taken independently of one another from hydrogen atom, alkyl, alkylheteroaryl and aralkyl group; or R₃ and R₄ in common with nitrogen atom bound with them form heteroaryl or heterocycloaryl substitute optionally substituted with one halogen atom, alkoxy group, aryl, heteroaryl and heterocycloalkyl; R₅ and R₆mean hydrogen atom. Also, invention relates to using the compound by any claims among 1-7 for preparing pharmaceutical compositions showing antibacterial properties, and to above said pharmaceutical compositions. Invention provides synthesis of novel compounds possessing useful biological properties, and a pharmaceutical composition based on thereof.

EFFECT: valuable medicinal properties of compounds and pharmaceutical composition.

9 cl, 8 ex

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RU 2 321 584 C2

Authors

Varshakun Namal Chizranga

Bush Rodni Dian

Dates

2008-04-10—Published

2003-11-07—Filed