METHOD FOR PREPARING METALLOORGANIC ORGANIC INTERMEDIATE COMPOUNDS Russian patent published in 2008 - IPC C07F1/02 

FIELD: chemistry of metalloorganic compounds, chemical technology.

SUBSTANCE: invention describes an improved method for synthesis of lithium-organic compounds providing in situ step in preparing aryl-lithium compounds of the formula IV and/or VI that compounds are subjected the for interaction with an electrophilic reagent. Compounds of the formula IV and/or V: are synthesized by interaction of halides of the formula I with metallic lithium to yield compound of the formula II followed by its interaction with compounds of the formula III and/or V, deprotonation to form lithium-containing compounds of the formula IV and/or VI (equation I) wherein R means -CH₃, primary, secondary or tertiary (C₂-C₈)-alkyl, unsubstituted (C₅-C₁₀)-cycloalkyl; X_1-4 means hydrogen atom (H), two residues near with X_1-4 R1-R4 form in common oxygen (O) or sulfur (S) atoms; R1-R4 and residue Z mean H, -CH₃, alkoxy, alkoxyalkyl, substituted acyclic alkyl or F; Hal means F, Br, Cl. Method is inexpensive, shows high yield and purity degree of end products. The 1-st step: synthesis of a base: . The 2-d step: deprotonation of substrate: .

EFFECT: improved method of synthesis.

9 cl, 6 ex