FIELD: experimental medicine.
SUBSTANCE: the present innovation deals with forming a wound of soft tissues being of 3.9-4.1 cm size in mature rabbits of about 3-4 kg body weight due to applying a plate onto their backs at internal diameter of ring being of 2.0 cm. The hide should be stretched under general anesthesia as a cone at 0.9-1.1 cm height to be dissected. Then it is necessary to form the focus of necrosis due to applying a gauze tampon impregnated in 70%-acetic acid solution for about 3-5 sec. In 3-5 d the necrotic scab should be removed. Then the wound should be irrigated with St. Aureus culture at concentration being 5×105 CFU. The innovation provides adequate reproduction of the model of bacterially contaminated wound of soft tissues without abscess development.
EFFECT: higher efficiency of modeling.
2 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF MODELLING INFECTED SKIN WOUND | 2010 |
|
RU2431890C1 |
| METHOD FOR MODELING INFECTED HEPATIC WOUND | 2004 |
|
RU2261482C1 |
| METHOD OF TREATING INFECTED WOUNDS IN EXPERIMENT | 2011 |
|
RU2466720C2 |
| METHOD OF PRODUCING LABORATORY MODEL OF ARTIFICIAL PHLEGMONOUS INFLAMMATION OF SOFT TISSUE IN RATS AGAINST BACKGROUND OF ARTIFICIAL IMMUNOSUPPRESSION | 2014 |
|
RU2581255C1 |
| PREPARATION FOR SOFT TISSUE REGENERATION WITH ANTIBACTERIAL EFFECT | 2012 |
|
RU2485959C1 |
| WOUND HEALING PRODUCT IN THE FORM OF AN OINTMENT CONTAINING RUBIDIUM CHLORIDE | 2019 |
|
RU2722127C1 |
| METHOD FOR SIMULATING ACUTE PURULENT DESTRUCTIVE COXITIS IN LABORATORY ANIMALS | 2012 |
|
RU2494468C1 |
| METHOD FOR TREATMENT OF WOUNDS AND PURULENT-NECROTIC LESIONS OF TOES OF FARM ANIMALS | 0 |
|
SU1706626A1 |
| METHOD FOR MODELING PYELONEPHRITIS | 2004 |
|
RU2289852C2 |
| COMPOSITE FOR ACCELERATED HEALING OF WOUNDS OF VARIOUS AETIOLOGIES, USE OF COMPOSITE AS COSMETIC AGENT AND AS A THERAPEUTIC AGENT IN VETERINARY SCIENCE, AGENT FOR SKIN REGENERATION BASED ON COMPOSITE | 2017 |
|
RU2693228C2 |
