METHOD OF PREOPERATIONAL DIAGNOSTICS AND PREVENTION OF HEMOCOAGULATION COMPLICATIONS Russian patent published in 2008 - IPC A61B10/00 G01N33/86 

FIELD: medicine, orthopedics and traumatology.

SUBSTANCE: method can be useful for early diagnostics and prevention of thromboembolism in hip and knee replacement in traumotologic, orthopedic, surgery hospital departments, clinics and research institutes. In preoperational period, antithrombin III is evaluated, sodium thiosulfate 10 ml is injected intravenously daily, at the same time cuff test is taken by blood sampling following tonometer's cuff application and pumping pressure equal to systolic, antithrombin III is evaluated in blood samples and if its level is not changed against the baseline preoperational preparation is taken with sodium thiosulfate injection until antithrombin III is elevated during cuff test. And at that, sodium thiosulfate can be injected during 5-8 days up to the moment when antithrombin III is increased 80% from baseline and positive dynamics in cuff test is maintained.

EFFECT: method increases impartiality and precision of preoperational diagnostics of thromboses and embolism.

3 cl, 3 tbl, 1 ex