3-PHENYLCINNOLIN ANALOGUE AND BASED ON IT ANTI-TUMOR AGENT Russian patent published in 2008 - IPC C07D237/28 C07D401/04 A61K31/502 A61P35/00 

FIELD: medicine; pharmacology.

SUBSTANCE: invention can be used in medicine and pharmaceutical industry and relates to the cell proliferation inhibitor and to the anti-tumor agent, which contains the 3-phenylcinnolin analogue as an active component, and has the formulas , where J presents the A-C-B, where C is carbon, A is alcoxy, OH, acyloxy or amino acid residue, B is hydrogen, alkyl group, carbonyl group or = N-NH₂ together with A, K - (CH₂)_q; L - N-W, where N -nitrogen atom, or W-C-W′, where C - carbon atom; W - alkyl group or hydrogen atom; W′ - alkyl, phenyl, carboxyl or alcoxycarbonyl group or hydrogen; J-K-L-M corresponds to C(O-Y)=CH-C(W)=CH or M - group (CH₂)_m; Z - oxygen; X - alcoxyl group, halogenated alkyl group, nitrogroup, cyanogroup or halogen; X' - halogen or hydrogen; m and q = 1, n and n' = 0 or 1, and (n + n') less than 2.

EFFECT: improved anti-tumor agent is available based on described compound.

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