STABLE PERORAL SUSPENSION OF NON-DIHYDRATED AZYTROMICINA Russian patent published in 2008 - IPC A61K9/10 A61K9/14 A61K31/7048 A61K47/26 A61K47/36 A61K47/38 

FIELD: medicine; chemical and pharmaceutical industry.

SUBSTANCE: invention relates to peroral suspension containing non-dihydrated azytromicina, accipient stabilizing conversion of azytromicina, and aqueous carrier. Also a method of inhibiting conversion of non-dihydrated azytromicina in the peroral suspension has been proposed by mixing a quantity of accipient reducing the surface tension with aqueous carrier and non-dihydrated azytromicina to produce the suspension where the quantity of accipient reducing the surface tension reduced tension in a volume of water equal to the certain volume of aqueous carrier to less than 50 dine/cm (5·10^-2 N/m). Besides, a method inhibiting conversion of non-dihydrated azytromicina in the peroral suspension has been proposed, where the peroral suspension contains no conversion accentuator by mixing the viscosity agent with the aqueous carrier and non-dihydrated azytromicina to make the peroral suspension with viscosity of approximately 3 cP (3 mPa·s) or more. A method has been proposed of treating bacterial and protozoal infections in patients by administering peroral suspension.

EFFECT: method inhibits conversion of a form of non-dihydrated azytromicina in peroral suspension.

12 cl, 5 ex, 14 tbl