DRUG COMPOSITIONS CONTAINING CONTROLLED RELEASE HYPROMELLOSE MATRIXES Russian patent published in 2011 - IPC A61K47/38 A61K47/32 A61K9/22 A61J3/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention aims at a controlled release composition for an oral solid dosage form. The composition contains mixed hypromellose and polyvinylacetatephthalate. An amount of hypromellose makes 8 to 60 wt %, an amount of polyvinylacetatephthalate is effective for maintaining controlled release of a pharmaceutically active ingredient in vitro and makes 4 to 60 wt % of the mixture. Said mixture of hypromellose and polyvinylacetatephthalate is pressed in a swelling hydrophilic matrix.

EFFECT: invention enables controlled release of the combined pharmaceutically active ingredient.

25 cl, 6 ex