DERIVATIVES OF 1-N-PHENYLAMINO-1H-IMIDAZOLE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Russian patent published in 2008 - IPC C07D233/54 A61K31/4164 A61P15/04 A61P43/00 

Abstract RU 2327691 C2

FIELD: chemistry; pharmaceutical compositions.

SUBSTANCE: imidazole derivatives have general formula (I) where each of R1 and R2 independently represents hydrogen, (C1-C6)alkyl or (C3-C8)cycloalkyl; n=0.1 or 2; each of R3, R4, R5 and R6 independently represents hydrogen or (C1-C6)alkyl, halogen, cyano, (C1-C6)alkoxy, trifluoromethyl, (C1-C6)alkylthio, (C1-C6)alkylsulphonyl or (C1-C6)alkoxycarbonyl; R3 and R6 together with their carrier phenyl ring can also form N-methylbenzotriazole and to its acidic-additive salts, solvates and stereoisomer forms. Also, the given invention relates to pharmaceutical compositions, inhibitory aromatiser and application of derived imidazole of formula (I) for producing of medication.

EFFECT: new compounds, with useful biological properties.

23 cl, 2 tbl, 33 ex

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RU 2 327 691 C2

Authors

Adzhe Natali

Bonne Pol'

Karniato Deni

Lafaj Zhan

Delansorn Remi

Paskal' Zhan-Klod

Dates

2008-06-27Published

2003-12-15Filed