FIELD: chemistry; medicine.
SUBSTANCE: invention pertains to derivatives of 7-phenylpyrazolopyridine with formula (I) 
,where R1, R5, R6, R40, R41 and R42 represent different hydrocarbon substitutes or functional groups, its salts or hydrates, and especially to salts of N-cyclopropylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyradin-3-yl-N-tetrahydro-2H-4-pyranylmethylamine. The compound with formula (I), especially salts of N-cyclopropylmethyl-N-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethylpyrazolo[1,5-a]pyradin-3-yl-N-tetrahydro-2H-4-pyranylmethylamine, act as antagonists of the receptor of corticotrophin release factor and can be used in medicine for treating various diseases of the nervous system and the gastrointestinal tract.
EFFECT: obtaining of new biologically active substances.
162 ex, 5 tbl
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| CYCLOPROPANE COMPOUNDS | 2011 |
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| NOVEL COMPOUNDS OF CONDENSED IMIDAZOLE POSSESSING OF CB2 RECEPTOR AGONIST PROPERTY | 2002 |
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| CONDENSED HETEROCYCLIC NITROGEN COMPOUNDS AND USING THEM AS INHIBITORS OF AMYLOID BETA PRODUCTION | 2010 |
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| CONDENSED HETEROCYCLIC COMPOUNDS | 2006 |
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| CYCLOALKANE DERIVATIVE | 2013 |
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| BENZOFURAN DERIVATIVES | 2004 |
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RU2328495C2 |
| NOVEL DERIVATIVE OF PURINYLPYRIDINYLAMINO-2,4-DIFLUOROPHENYLSULPHONAMIDE, ITS PHARMACEUTICALLY ACCEPTABLE SALT, METHOD OF ITS OBTAINING AND PHARMACEUTICAL COMPOSITION, WHICH HAS INHIBITION ACTIVITY WITH RESPECT TO RAF-KINASE, CONTAINING CLAIMED COMPOUND AS ACTIVE INGREDIENT | 2011 |
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| CONDENSED AMINOHYDROTHIAZINE DERIVATIVE | 2009 |
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| 6-5 CONDENSED RINGS AS C5a INHIBITORS | 2018 |
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RU2780338C2 |
