FIELD: chemistry.
SUBSTANCE: invention relates to the new crystalline modification of 2-(3, 5- bis-trifluoromethylphenyl)-H-[6-(1, 1-dioxo-1λ6 -thiomorphyline-4-yl)-4-(fluoro-2-methylphenyl)pyridine-3-yl]-N-methylisobutypiramide, which is characterised by the following parameters of the X-ray diffractogram, obtained with the use of CuKα radiation, with the values 2θ (angle 2 theta), equals 4.5, 6.4, 7.5, 7.7, 8.0, 8.2, 10.0, 10.2, 10.9, 11.1, 12.9, 13.4, 14.0, 14.5, 15.1, 15.6, 16.2, 16.5, 17.3, 17.5, 18.0, 18.9, 19.3, 19.5, 19.9, 20.1, 20.6, 21.0, 21.4, 22.7, 23.1 and 23.6 and by the infra-red spectrum in which there are characteristic strips at 2925, 2854, 1637, 1604, 1484, 1395, 1375, 1285, 1230, 1172, 1125, 1082, 999, 943, 893, 868, 860, 782, 705, 684 cm-1, and having the extrapolated melting point (according to the data of differential scanning calorimetry), the component of 137.2°C.
EFFECT: relates to a pharmaceutical composition on the basis of the new crystalline modification.
3 cl, 8 dwg, 5 tbl, 2 ex
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