SOLID FORMS OF (1,1-DIOXO-4-THIOMORPHOLINYL) - [6 - [[3- (4-FLUOROPHENYL) -5-METHYL-4-ISOXAZOLYL] METHOXY] -3-PYRIDINYL] METHANONE Russian patent published in 2017 - IPC C07D401/12 A61K31/541 A61P25/28 

Abstract RU 2618524 C2

FIELD: chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, in particular to a new solid form of the compound of formula (I). The invention also relates to a process for preparing of the said solid forms, pharmaceutical compositions based on the solid form, the use of solid forms of the compound (I) and a method of treating or preventing disorders associated with GABA A α5 receptor.

EFFECT: invention provides obtaining of a new solid form of the compound (I), having improved stability, good bioavailability and low hygroscopic property.

13 cl, 23 dwg, 7 tbl, 28 ex

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RU 2 618 524 C2

Authors

Dott Paskal

Grassmann Olaf

Kammerer Mikhel

Manns Ioakhim

Shvitter Urs

Tomas Endryu

Vittenbakh Nikol

Dates

2017-05-04Published

2012-10-17Filed