POLYMORPHYSM OF DODECAHYDROCYCLOPENTA[A] PHENANTRENYL ETHER OF THIOPHENECARBOXYLIC ACID Russian patent published in 2008 - IPC C07J33/00 A61K31/58 A61P11/00 

Abstract RU 2330043 C2

FIELD: chemistry.

SUBSTANCE: described is a new polymorphous crystalline form B (6S, 9R, 10S, 11S, 13 S, 16R, 17R)-9-chlorine-6-fluorine-11-hydroxy-17-methoxycarbonyl-10,13,16-trimethyl-3-oxo-6,7,8,9,10,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenantrene-17-ylic ether-3-methylthiophene-2-carboxylic acid. Also described are methods of obtaining it.

EFFECT: crystalline form with high antipyretic activity and high stability.

5 cl, 5 ex, 7 tbl, 2 dwg

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RU 2 330 043 C2

Authors

Jordine Guido

Mutts Mikhaehl'

Dates

2008-07-27Published

2003-07-28Filed