POLYMORPHYSM OF DODECAHYDROCYCLOPENTA[A]PHENANTRENYL ETHER OF THIOPHENECARBOXYLIC ACID Russian patent published in 2009 - IPC C07J33/00 A61K31/58 A61P11/00 

Abstract RU 2348646 C1

FIELD: chemistry.

SUBSTANCE: invention concerns crystalline form A of compound of the formula I, method of its obtainment and application in medicine. Form A can be obtained by crystallisation of compound of the formula I from solution in isopropanol, ethylacetate, n-butanol, hexane, heptane, tertbutylmethyl ether, toluene or tetrahydrofurane, and features melting point at 264°C along with degradation at heating rate of 20°C/minute by data of differential scanning calorimetry, and diffraction bands (2θ at angular degrees ±0.2°): 3.6°, 7.3°, 13.4°, 14.6°, 18.3°, 22.0°, 25.8°, 25.9° and 29.5°, according to the data of x-ray structural analysis. .

EFFECT: obtaining stable form of compound of the formula I with anti-inflammation effect.

4 cl, 5 ex, 7 tbl

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RU 2 348 646 C1

Authors

Jordine Guido

Mutts Mikhaehl'

Dates

2009-03-10Published

2003-07-28Filed