AVERMECTIN B1 AND AVERMEKTINE B1 MONOSACCHARIDE DERIVATIVES WITH ALKOXYMETHYL SUBSTITUTE IN THE POSITION 4"- OR 4'- Russian patent published in 2008 - IPC C07H17/08 A01N43/90 A01P7/04 

FIELD: chemistry.

SUBSTANCE: invention concerns avermectin B1 and avermectin B1 monosaccharide derivatives of the general formula I , where n is 0 or 1; A- B is -CH=CH- or -CH₂-CH₂-; R¹ is C₁-C₈-alkyl, C₃-C₈-cycloalkyl or C₂-C₈-alkenyl; R² is C₁-C₈-alkyl or C₂-C₈-alkenyl, optionally substituted by a subsitutde selected out of the group of -OH, - N₃, -NO₂, C₁-C₈-alkoxy-, C₁-C₆-alkoxy-C₁-C₆-alkoxy, C₁-C₈-alkylthio, C₁-C₈-alkylsulfinyl, C₁-C₈-alkylsulfonyl, -NR₄R₆, -X- C(=Y)-R₄, -X-C(=Y)-Z-R₄, or phenyl substituted optionally by halogen; R₃ is H or C₁-C₈-alkyl substituted by halogen; or R₂ and R₃ together are a 3-7-membered alkylene bridge substituted optionally by C₁-C₄-alkyl, or form together a -CH₂-CH₂-O-CH₂- or -CH₂-CH₂-C(=O)-CH₂- group; X is -O- or NR₅; Y is -O-; Z is -O-; R₄ is hydrogen or C₁-C₈-alkyl substituted optionally by C₁-C₆-alkoxy; R₅ is hydrogen or C₁-C₈-alkyl; R₆ is hydrogen or C_1-8-alkyl if the compound is not a avermectin B1a or B1b derivative where n is 1, R₃ is H and R₂ is -CH₂-CH₂-OCH₃ or -CH₂-CH₂-O-phenyl; and is not a B1a or B1b derivative where n is 1, and R₂ and R₃ form together an unsubstituted -CH₂-CH₂-CH₂- group; while their E/Z isomers, mixes of E/Z isomers and/or tautomers, in a free or salt form in each case.

EFFECT: production of insecticide composition and method of cultivated plant pest eradication.

7 cl, 5 tbl, 27 ex