FIELD: chemistry, pharmaceutical.
SUBSTANCE: invention pertains to new tetracyclic compounds containing a heteroatom. The compounds can be used in treating and/or prevention of disorders, associated with oestrogen depletion, such as hot flash, vaginal dryness, osteopenia and osteoporosis; sensitive cancerous diseases hormone and hyperplasia of the lacteal gland, endometrium, cervix uteri and prostate; endometriosis, uterus fibrosis and osteoarthritis, and as contraceptive agents, used either separately or combined with progestogen or a progestogen antagonist.
EFFECT: obtaining tetracyclic compounds containing a heteroatom used in treatment and/or prevention of disorders, associated with depletion of oestrogen.
5 cl, 8 tbl, 176 ex
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